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If you want the broader landscape (and the list of other peptides driving search interest), see Meto’s internal piece: “14 Peptides Are About to Become Legal Again — What This Means for Your Health.” Who should consider AOD-9604 (and who shouldn’t) Consider it only if your expectations are realistic AOD-9604 may be worth a conversation if you are: Already doing the fundamentals (protein, resistance training, sleep) Not seeking massive scale weight loss Looking at fat-loss support rather than appetite suppression Intolerant of GLP-1s and exploring alternatives (with the understanding that alternatives are usually less powerful) Avoid it if… You have significant obesity and need a high-efficacy therapy (GLP-1/GIP class is typically far more impactful) (PubMed) You’re hoping it will “melt fat” without dietary alignment Your plan depends on unverified sources or “research peptide” suppliers You’re in a drug-tested sport environment (WADA prohibition is relevant) (wada-ama.org) Practical expectations (what most people want to know) How fast does it work

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PMID: 33015921 Nat Metab 2025 Apr;7(4):730-741